Prediction of New-Onset and Recurrent Atrial Fibrillation by Complete Blood Count Tests: A Comprehensive Systematic Review with Meta-Analysis

BACKGROUND Atrial fibrillation (AF) is one of the most critical and frequent arrhythmias precipitating morbidities and mortalities. The complete blood count (CBC) test is an important blood test in clinical practice and is routinely used in the workup of cardiovascular diseases. This systematic revi...

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Veröffentlicht in:MEDICAL SCIENCE MONITOR BASIC RESEARCH 2017-05, Vol.23, p.179-222
Hauptverfasser: Weymann, Alexander, Ali-Hasan-Al-Saegh, Sadeq, Sabashnikov, Anton, Popov, Aron-Frederik, Mirhosseini, Seyed Jalil, Liu, Tong, Lotfaliani, Mohammadreza, Sá, Michel Pompeu Barros de Oliveira, Baker, William L L, Yavuz, Senol, Zeriouh, Mohamed, Jang, Jae-Sik, Dehghan, Hamidreza, Meng, Lei, Testa, Luca, D'Ascenzo, Fabrizio, Benedetto, Umberto, Tse, Gary, Nombela-Franco, Luis, Dohmen, Pascal M, Deshmukh, Abhishek J, Linde, Cecilia, Biondi-Zoccai, Giuseppe, Stone, Gregg W, Calkins, Hugh, Surgery And Cardiology-Group Imcsc-Group, Integrated Meta-Analysis Of Cardiac
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Sprache:eng
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Zusammenfassung:BACKGROUND Atrial fibrillation (AF) is one of the most critical and frequent arrhythmias precipitating morbidities and mortalities. The complete blood count (CBC) test is an important blood test in clinical practice and is routinely used in the workup of cardiovascular diseases. This systematic review with meta-analysis aimed to determine the strength of evidence for evaluating the association of hematological parameters in the CBC test with new-onset and recurrent AF. MATERIAL AND METHODS We conducted a meta-analysis of observational studies evaluating hematologic parameters in patients with new-onset AF and recurrent AF. A comprehensive subgroup analysis was performed to explore potential sources of heterogeneity. RESULTS The literature search of all major databases retrieved 2150 studies. After screening, 70 studies were analyzed in the meta-analysis on new-onset AF and 23 studies on recurrent AF. Pooled analysis on new-onset AF showed platelet count (PC) (weighted mean difference (WMD)=WMD of -26.39×10^9/L and p
ISSN:2325-4416
2325-4394
2325-4416
DOI:10.12659/MSMBR.903320