Dietary antioxidants and risk of Parkinson's disease in two population‐based cohorts

ABSTRACT Background: A neuroprotective effect of dietary antioxidants on Parkinson's disease (PD) risk has been suggested, but epidemiological evidence is limited. Objectives: To examine the associations between intake of dietary antioxidant vitamins and total antioxidant capacity and risk of P...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Movement disorders 2017-11, Vol.32 (11), p.1631-1636
Hauptverfasser:	Yang, Fei, Wolk, Alicja, Håkansson, Niclas, Pedersen, Nancy L., Wirdefeldt, Karin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antioxidants Antioxidants - administration & dosage Antioxidants - pharmacology Ascorbic acid Ascorbic Acid - administration & dosage Ascorbic Acid - pharmacology beta Carotene - administration & dosage beta Carotene - pharmacology Brief Report Brief Reports Diet Dietary intake Female Follow-Up Studies Humans Male Middle Aged Movement disorders Neurodegenerative diseases Neuroprotection Neuroprotective Agents - administration & dosage Neuroprotective Agents - pharmacology Parkinson Disease - epidemiology Parkinson Disease - prevention & control Parkinson's disease risk factors Sex Factors Sweden - epidemiology Vitamin E Vitamin E - administration & dosage Vitamin E - pharmacology Vitamins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	ABSTRACT Background: A neuroprotective effect of dietary antioxidants on Parkinson's disease (PD) risk has been suggested, but epidemiological evidence is limited. Objectives: To examine the associations between intake of dietary antioxidant vitamins and total antioxidant capacity and risk of PD. Methods: We prospectively assessed the relationships of dietary antioxidant vitamins C and E, ß‐carotene, and total antioxidant capacity with PD risk in two population‐based cohorts (38,937 women and 45,837 men). Results: During a mean 14.9‐year follow‐up period, 1,329 PD cases were identified. Dietary intake of ß‐carotene was associated with a lower risk of PD (hazard ratio: 0.86; 95% confidence interval: 0.78‐0.95; Ptrend
ISSN:	0885-3185 1531-8257 1531-8257
DOI:	10.1002/mds.27120