Childhood onset inflammatory bowel disease and risk of cancer: a Swedish nationwide cohort study 1964-2014

Objective To assess risk of cancer in patients with childhood onset inflammatory bowel disease in childhood and adulthood.Design Cohort study with matched general population reference individuals using multivariable Cox regression to estimate hazard ratios.Setting Swedish national patient register (...

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Veröffentlicht in:	BMJ (Online) 2017-09, Vol.358, p.j3951-j3951
Hauptverfasser:	Olén, O, Askling, J, Sachs, MC, Frumento, P, Neovius, M, Smedby, KE, Ekbom, A, Malmborg, P, Ludvigsson, JF
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Cancer Child Children Classification Cohort analysis Cohort Studies Colitis, Ulcerative - epidemiology Colitis, Ulcerative - therapy Colorectal cancer Comorbidity Crohn Disease - epidemiology Crohn Disease - therapy Crohn's disease Female Gastroenterology Gastrointestinal cancer Gastrointestinal Neoplasms - epidemiology Health risk assessment Humans Incidence Inflammatory bowel disease Inflammatory bowel diseases Intestine Lymphoma Lymphoma - epidemiology Male Melanoma Neoplasms - epidemiology Patients Population Population studies Risk assessment Risk Factors Skin cancer Skin Neoplasms - epidemiology Surveillance Sweden - epidemiology Ulcerative colitis
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Zusammenfassung:	Objective To assess risk of cancer in patients with childhood onset inflammatory bowel disease in childhood and adulthood.Design Cohort study with matched general population reference individuals using multivariable Cox regression to estimate hazard ratios.Setting Swedish national patient register (both inpatient and non-primary outpatient care) 1964-2014.Participants Incident cases of childhood onset (
ISSN:	1756-1833 0959-8138 0959-535X 1756-1833
DOI:	10.1136/bmj.j3951