Reduced CDHR3 expression in children wheezing with rhinovirus

Background Rhinovirus‐induced wheezing in young children has been associated with increased asthma risk at school age. Recently, the transmembrane protein cadherin‐related family member 3 (CDHR3) was identified as the RV‐C receptor and the genetic variant rs6967330 (p.Cys529Tyr) was reported to be a...

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Veröffentlicht in:	Pediatric allergy and immunology 2018-03, Vol.29 (2), p.200-206
Hauptverfasser:	Stenberg Hammar, Katarina, Niespodziana, Katarzyna, van Hage, Marianne, Kere, Juha, Valenta, Rudolf, Hedlin, Gunilla, Söderhäll, Cilla
Format:	Artikel
Sprache:	eng
Schlagworte:	acute wheezing Asthma Cadherins Cadherins - metabolism cadherin‐related family member 3 Child, Preschool Children Female Gene expression Gene Frequency Genetic diversity Genetic Predisposition to Disease Genetic variance Genotype Genotypes Humans Infant Leukocytes Longitudinal Studies Male Membrane Proteins - metabolism mRNA expression Peripheral blood peripheral blood leukocytes Permeability Phenotypes Picornaviridae Infections - metabolism Preschool children Respiratory Sounds - genetics Rhinovirus Rhinovirus - genetics Risk rs6967330 Wheezing
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