Calculation Algorithm Reduces Protamine Doses Without Increasing Blood Loss or the Transfusion Rate in Cardiac Surgery: Results of a Randomized Controlled Trial

The aim of the study was to investigate whether the HeProCalc algorithm affects heparin and protamine dosage, postoperative blood loss, and transfusion rate. Randomized controlled trial. University hospital. The study comprised 210 cardiac surgery patients undergoing cardiac surgery with cardiopulmo...

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Veröffentlicht in:Journal of cardiothoracic and vascular anesthesia 2019-04, Vol.33 (4), p.985-992
Hauptverfasser: Kjellberg, Gunilla, Holm, Manne, Fux, Thomas, Lindvall, Gabriella, van der Linden, Jan
Format: Artikel
Sprache:eng
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Zusammenfassung:The aim of the study was to investigate whether the HeProCalc algorithm affects heparin and protamine dosage, postoperative blood loss, and transfusion rate. Randomized controlled trial. University hospital. The study comprised 210 cardiac surgery patients undergoing cardiac surgery with cardiopulmonary bypass. Twenty patients were excluded because of re-exploration for localized surgical bleeding (n = 9), violation of protocol (n = 2), aprotinin use (n = 3 and nadir body temperature
ISSN:1053-0770
1532-8422
1532-8422
DOI:10.1053/j.jvca.2018.07.044