The Enigmatic “Indirect Pathway” of the Basal Ganglia: A New Role

Goal-directed behavior is processed in the dorsomedial striatum. Using a probabilistic reward paradigm, Nonomura et al. (2018) show that indirect pathway neurons signal when an action is incorrect and it is time to switch strategies, while the direct pathway remains active with a correct action. Goa...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2018-09, Vol.99 (6), p.1105-1107
1. Verfasser:	Grillner, Sten
Format:	Artikel
Sprache:	eng
Schlagworte:	Basal Ganglia Corpus Striatum Dopamine Goals Laboratories Medicin och hälsovetenskap Neostriatum Neurons Reinforcement Reward
Online-Zugang:	Volltext
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Zusammenfassung:	Goal-directed behavior is processed in the dorsomedial striatum. Using a probabilistic reward paradigm, Nonomura et al. (2018) show that indirect pathway neurons signal when an action is incorrect and it is time to switch strategies, while the direct pathway remains active with a correct action. Goal-directed behavior is processed in the dorsomedial striatum. Using a probabilistic reward paradigm, Nonomura et al. (2018) show that indirect pathway neurons signal when an action is incorrect and it is time to switch strategies, while the direct pathway remains active with a correct action.
ISSN:	0896-6273 1097-4199 1097-4199
DOI:	10.1016/j.neuron.2018.08.040