Prospective International Study of Incidence and Predictors of Immune Reconstitution Inflammatory Syndrome and Death in People Living With Human Immunodeficiency Virus and Severe Lymphopenia

Abstract Background Patients living with human immunodeficiency virus (PLWH) with low CD4 counts are at high risk for immune reconstitution inflammatory syndrome (IRIS) and death at antiretroviral therapy (ART) initiation. Methods We investigated the clinical impact of IRIS in PLWH and CD4 counts

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Veröffentlicht in:	Clinical infectious diseases 2020-07, Vol.71 (3), p.652-660
Hauptverfasser:	Sereti, Irini, Sheikh, Virginia, Shaffer, Douglas, Phanuphak, Nittaya, Gabriel, Erin, Wang, Jing, Nason, Martha C, Roby, Gregg, Ngeno, Hellen, Kirui, Fredrick, Pau, Alice, Mican, Joann M, Rupert, Adam, Bishop, Rachel, Agan, Brian, Chomchey, Nitiya, Teeratakulpisarn, Nipat, Tansuphaswadikul, Somsit, Langat, Deborah, Kosgei, Josphat, French, Martyn, Ananworanich, Jintanat, Sawe, Fredrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and Commentaries CD4 Lymphocyte Count Female HIV HIV Infections - complications HIV Infections - drug therapy Humans Immune Reconstitution Inflammatory Syndrome - epidemiology Incidence Kenya Lymphopenia - epidemiology Male Prospective Studies Thailand
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Zusammenfassung:	Abstract Background Patients living with human immunodeficiency virus (PLWH) with low CD4 counts are at high risk for immune reconstitution inflammatory syndrome (IRIS) and death at antiretroviral therapy (ART) initiation. Methods We investigated the clinical impact of IRIS in PLWH and CD4 counts
ISSN:	1058-4838 1537-6591 1537-6591
DOI:	10.1093/cid/ciz877