Maternal education and language development at 2 years corrected age in children born very preterm: results from a European population-based cohort study

BackgroundSocioeconomic factors influence language development in the general population, but the association remains poorly documented in children born very preterm (VPT). We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal...

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Veröffentlicht in:Journal of epidemiology and community health (1979) 2020-04, Vol.74 (4), p.346-353
Hauptverfasser: Sentenac, Mariane, Johnson, Samantha, Charkaluk, Marie-Laure, Sëppanen, Anna-Veera, Aden, Ulrika, Cuttini, Marina, Maier, Rolf, Mannamaa, Mairi, Zeitlin, Jennifer
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container_issue 4
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container_title Journal of epidemiology and community health (1979)
container_volume 74
creator Sentenac, Mariane
Johnson, Samantha
Charkaluk, Marie-Laure
Sëppanen, Anna-Veera
Aden, Ulrika
Cuttini, Marina
Maier, Rolf
Mannamaa, Mairi
Zeitlin, Jennifer
description BackgroundSocioeconomic factors influence language development in the general population, but the association remains poorly documented in children born very preterm (VPT). We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal risk.MethodsData were from the Effective Perinatal Intensive Care in Europe (EPICE) population-based cohort of children born
doi_str_mv 10.1136/jech-2019-213564
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We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal risk.MethodsData were from the Effective Perinatal Intensive Care in Europe (EPICE) population-based cohort of children born &lt;32 weeks’ gestational age (GA) in 2011/2012. Regions from six countries (Estonia, France, Germany, Italy, Sweden and UK) used a validated short form MacArthur Developmental Communicative Inventories Checklist to assess language at 2 years corrected age. Perinatal variables were collected from clinical records. We assessed expressive language delay (ELD), defined as (a) not combining words; and (b) expressive vocabulary &lt;10th percentile of norms for age and sex. Perinatal risk (low, moderate and high) was determined using GA, small for GA and neonatal morbidities. We estimated adjusted risk ratios (aRR) of ELD by maternal education with inverse weighting to account for non-response bias.ResultsOf 2741 children, 24.6% were not combining words and 39.7% had a low expressive vocabulary. Low maternal education (lower secondary or less compared with a bachelor’s degree or more) increased risks of ELD: not combining words: aRR=1.52 (95% CI 1.36 to 1.69); low expressive vocabulary: aRR=1.25 (1.04 to 1.51). For children with low perinatal risk, the aRR were 1.88 (1.26 to 2.80) and 1.44 (1.06 to 1.95), respectively, compared with those with high perinatal risks: 1.36 (1.10 to 1.67) and 1.11 (0.97 to 1.27), respectively.ConclusionLow maternal education affects ELD for children born VPT, although the association appears attenuated among those with highest perinatal risk.</description><identifier>ISSN: 0143-005X</identifier><identifier>ISSN: 1470-2738</identifier><identifier>EISSN: 1470-2738</identifier><identifier>DOI: 10.1136/jech-2019-213564</identifier><identifier>PMID: 31996408</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Age ; Bilingualism ; Birth weight ; Child, Preschool ; Children ; Children &amp; youth ; Cohort analysis ; Cohort Studies ; Country of birth ; Education ; Educational Status ; Europe ; Families &amp; family life ; Female ; Gestational Age ; Humans ; Infant, Extremely Premature ; Infant, Newborn ; Language ; Language Development ; Language policy ; Life Sciences ; Male ; Medical prognosis ; Medicin och hälsovetenskap ; Mothers - psychology ; Multiple births ; Neonates ; Parent educational background ; Population ; Population studies ; Population Surveillance ; Population-based studies ; Pregnancy ; Premature birth ; Questionnaires ; Santé publique et épidémiologie ; Sociodemographics ; Socioeconomic Factors ; Socioeconomics</subject><ispartof>Journal of epidemiology and community health (1979), 2020-04, Vol.74 (4), p.346-353</ispartof><rights>Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2020 Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b557t-1c4a0876705063adc23d69d6cb5c5e76334c74ad9be965e72330cab324fc91a33</citedby><cites>FETCH-LOGICAL-b557t-1c4a0876705063adc23d69d6cb5c5e76334c74ad9be965e72330cab324fc91a33</cites><orcidid>0000-0002-3284-6874 ; 0000-0001-5234-6474 ; 0000-0001-5615-0639 ; 0000-0002-9568-2969 ; 0000-0002-2156-154X ; 0000-0002-6972-3608 ; 0000-0002-0650-3173 ; 0000-0001-8963-7881</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,781,785,886,27926,27927</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31996408$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://inserm.hal.science/inserm-02504009$$DView record in HAL$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:144622102$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Sentenac, Mariane</creatorcontrib><creatorcontrib>Johnson, Samantha</creatorcontrib><creatorcontrib>Charkaluk, Marie-Laure</creatorcontrib><creatorcontrib>Sëppanen, Anna-Veera</creatorcontrib><creatorcontrib>Aden, Ulrika</creatorcontrib><creatorcontrib>Cuttini, Marina</creatorcontrib><creatorcontrib>Maier, Rolf</creatorcontrib><creatorcontrib>Mannamaa, Mairi</creatorcontrib><creatorcontrib>Zeitlin, Jennifer</creatorcontrib><creatorcontrib>the EPICE group</creatorcontrib><title>Maternal education and language development at 2 years corrected age in children born very preterm: results from a European population-based cohort study</title><title>Journal of epidemiology and community health (1979)</title><addtitle>J Epidemiol Community Health</addtitle><description>BackgroundSocioeconomic factors influence language development in the general population, but the association remains poorly documented in children born very preterm (VPT). We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal risk.MethodsData were from the Effective Perinatal Intensive Care in Europe (EPICE) population-based cohort of children born &lt;32 weeks’ gestational age (GA) in 2011/2012. Regions from six countries (Estonia, France, Germany, Italy, Sweden and UK) used a validated short form MacArthur Developmental Communicative Inventories Checklist to assess language at 2 years corrected age. Perinatal variables were collected from clinical records. We assessed expressive language delay (ELD), defined as (a) not combining words; and (b) expressive vocabulary &lt;10th percentile of norms for age and sex. Perinatal risk (low, moderate and high) was determined using GA, small for GA and neonatal morbidities. We estimated adjusted risk ratios (aRR) of ELD by maternal education with inverse weighting to account for non-response bias.ResultsOf 2741 children, 24.6% were not combining words and 39.7% had a low expressive vocabulary. Low maternal education (lower secondary or less compared with a bachelor’s degree or more) increased risks of ELD: not combining words: aRR=1.52 (95% CI 1.36 to 1.69); low expressive vocabulary: aRR=1.25 (1.04 to 1.51). For children with low perinatal risk, the aRR were 1.88 (1.26 to 2.80) and 1.44 (1.06 to 1.95), respectively, compared with those with high perinatal risks: 1.36 (1.10 to 1.67) and 1.11 (0.97 to 1.27), respectively.ConclusionLow maternal education affects ELD for children born VPT, although the association appears attenuated among those with highest perinatal risk.</description><subject>Age</subject><subject>Bilingualism</subject><subject>Birth weight</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Children &amp; youth</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Country of birth</subject><subject>Education</subject><subject>Educational Status</subject><subject>Europe</subject><subject>Families &amp; family life</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Humans</subject><subject>Infant, Extremely Premature</subject><subject>Infant, Newborn</subject><subject>Language</subject><subject>Language Development</subject><subject>Language policy</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Medicin och hälsovetenskap</subject><subject>Mothers - psychology</subject><subject>Multiple births</subject><subject>Neonates</subject><subject>Parent educational background</subject><subject>Population</subject><subject>Population studies</subject><subject>Population Surveillance</subject><subject>Population-based studies</subject><subject>Pregnancy</subject><subject>Premature birth</subject><subject>Questionnaires</subject><subject>Santé publique et épidémiologie</subject><subject>Sociodemographics</subject><subject>Socioeconomic Factors</subject><subject>Socioeconomics</subject><issn>0143-005X</issn><issn>1470-2738</issn><issn>1470-2738</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkk9rFDEYxgdRbK3ePUnAi6Cj-TfJprdSqhVWvCh4C5nk3e6sM5Mxf1b2o_htzTjbioJ4ykv4_Z6E5KmqpwS_JoSJNzuw25piompKWCP4veqUcIlrKtnqfnWKCWc1xs2Xk-pRjDtcRknVw-qEEaUEx6vT6scHkyCMpkfgsjWp8yMyo0O9GW-yuQHkYA-9nwYYEzIJUXQAEyKyPgSwCRyaoW5Edtv1LsCIWh9GtIdwQFOAkj2cowAx9ymiTfADMugqBz-BGdHkp9z_OrNuTSxZ1m99SCim7A6Pqwcb00d4clzPqs9vrz5dXtfrj-_eX16s67ZpZKqJ5QavpJC4wYIZZylzQjlh28Y2IAVj3EpunGpBibJBGcPWtIzyjVXEMHZW1Utu_A5TbvUUusGEg_am08etr2UCzSVThBZe_ZOfgne_pVuRcC4oJXh2Xy3u1vR_iNcXa92NsbyWxrTBHGO1JwV_seAl91uGmPTQRQt9-RzwOWrK-EoqpYgs6PO_0J3P87_OlGxEg5mcKbxQNvgYA2zuLkGwnhul50bpuVF6aVRRnh2DczuAuxNuK1SAlwvQDrv_x_0E5dzXeg</recordid><startdate>20200401</startdate><enddate>20200401</enddate><creator>Sentenac, Mariane</creator><creator>Johnson, Samantha</creator><creator>Charkaluk, Marie-Laure</creator><creator>Sëppanen, Anna-Veera</creator><creator>Aden, Ulrika</creator><creator>Cuttini, Marina</creator><creator>Maier, Rolf</creator><creator>Mannamaa, Mairi</creator><creator>Zeitlin, Jennifer</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><scope>ADTPV</scope><scope>AOWAS</scope><orcidid>https://orcid.org/0000-0002-3284-6874</orcidid><orcidid>https://orcid.org/0000-0001-5234-6474</orcidid><orcidid>https://orcid.org/0000-0001-5615-0639</orcidid><orcidid>https://orcid.org/0000-0002-9568-2969</orcidid><orcidid>https://orcid.org/0000-0002-2156-154X</orcidid><orcidid>https://orcid.org/0000-0002-6972-3608</orcidid><orcidid>https://orcid.org/0000-0002-0650-3173</orcidid><orcidid>https://orcid.org/0000-0001-8963-7881</orcidid></search><sort><creationdate>20200401</creationdate><title>Maternal education and language development at 2 years corrected age in children born very preterm: results from a European population-based cohort study</title><author>Sentenac, Mariane ; 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We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal risk.MethodsData were from the Effective Perinatal Intensive Care in Europe (EPICE) population-based cohort of children born &lt;32 weeks’ gestational age (GA) in 2011/2012. Regions from six countries (Estonia, France, Germany, Italy, Sweden and UK) used a validated short form MacArthur Developmental Communicative Inventories Checklist to assess language at 2 years corrected age. Perinatal variables were collected from clinical records. We assessed expressive language delay (ELD), defined as (a) not combining words; and (b) expressive vocabulary &lt;10th percentile of norms for age and sex. Perinatal risk (low, moderate and high) was determined using GA, small for GA and neonatal morbidities. We estimated adjusted risk ratios (aRR) of ELD by maternal education with inverse weighting to account for non-response bias.ResultsOf 2741 children, 24.6% were not combining words and 39.7% had a low expressive vocabulary. Low maternal education (lower secondary or less compared with a bachelor’s degree or more) increased risks of ELD: not combining words: aRR=1.52 (95% CI 1.36 to 1.69); low expressive vocabulary: aRR=1.25 (1.04 to 1.51). For children with low perinatal risk, the aRR were 1.88 (1.26 to 2.80) and 1.44 (1.06 to 1.95), respectively, compared with those with high perinatal risks: 1.36 (1.10 to 1.67) and 1.11 (0.97 to 1.27), respectively.ConclusionLow maternal education affects ELD for children born VPT, although the association appears attenuated among those with highest perinatal risk.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>31996408</pmid><doi>10.1136/jech-2019-213564</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-3284-6874</orcidid><orcidid>https://orcid.org/0000-0001-5234-6474</orcidid><orcidid>https://orcid.org/0000-0001-5615-0639</orcidid><orcidid>https://orcid.org/0000-0002-9568-2969</orcidid><orcidid>https://orcid.org/0000-0002-2156-154X</orcidid><orcidid>https://orcid.org/0000-0002-6972-3608</orcidid><orcidid>https://orcid.org/0000-0002-0650-3173</orcidid><orcidid>https://orcid.org/0000-0001-8963-7881</orcidid><oa>free_for_read</oa></addata></record>
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source MEDLINE; JSTOR Archive Collection A-Z Listing
subjects Age
Bilingualism
Birth weight
Child, Preschool
Children
Children & youth
Cohort analysis
Cohort Studies
Country of birth
Education
Educational Status
Europe
Families & family life
Female
Gestational Age
Humans
Infant, Extremely Premature
Infant, Newborn
Language
Language Development
Language policy
Life Sciences
Male
Medical prognosis
Medicin och hälsovetenskap
Mothers - psychology
Multiple births
Neonates
Parent educational background
Population
Population studies
Population Surveillance
Population-based studies
Pregnancy
Premature birth
Questionnaires
Santé publique et épidémiologie
Sociodemographics
Socioeconomic Factors
Socioeconomics
title Maternal education and language development at 2 years corrected age in children born very preterm: results from a European population-based cohort study
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