Maternal education and language development at 2 years corrected age in children born very preterm: results from a European population-based cohort study
BackgroundSocioeconomic factors influence language development in the general population, but the association remains poorly documented in children born very preterm (VPT). We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal...
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Veröffentlicht in: | Journal of epidemiology and community health (1979) 2020-04, Vol.74 (4), p.346-353 |
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description | BackgroundSocioeconomic factors influence language development in the general population, but the association remains poorly documented in children born very preterm (VPT). We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal risk.MethodsData were from the Effective Perinatal Intensive Care in Europe (EPICE) population-based cohort of children born |
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We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal risk.MethodsData were from the Effective Perinatal Intensive Care in Europe (EPICE) population-based cohort of children born <32 weeks’ gestational age (GA) in 2011/2012. Regions from six countries (Estonia, France, Germany, Italy, Sweden and UK) used a validated short form MacArthur Developmental Communicative Inventories Checklist to assess language at 2 years corrected age. Perinatal variables were collected from clinical records. We assessed expressive language delay (ELD), defined as (a) not combining words; and (b) expressive vocabulary <10th percentile of norms for age and sex. Perinatal risk (low, moderate and high) was determined using GA, small for GA and neonatal morbidities. We estimated adjusted risk ratios (aRR) of ELD by maternal education with inverse weighting to account for non-response bias.ResultsOf 2741 children, 24.6% were not combining words and 39.7% had a low expressive vocabulary. Low maternal education (lower secondary or less compared with a bachelor’s degree or more) increased risks of ELD: not combining words: aRR=1.52 (95% CI 1.36 to 1.69); low expressive vocabulary: aRR=1.25 (1.04 to 1.51). For children with low perinatal risk, the aRR were 1.88 (1.26 to 2.80) and 1.44 (1.06 to 1.95), respectively, compared with those with high perinatal risks: 1.36 (1.10 to 1.67) and 1.11 (0.97 to 1.27), respectively.ConclusionLow maternal education affects ELD for children born VPT, although the association appears attenuated among those with highest perinatal risk.</description><identifier>ISSN: 0143-005X</identifier><identifier>ISSN: 1470-2738</identifier><identifier>EISSN: 1470-2738</identifier><identifier>DOI: 10.1136/jech-2019-213564</identifier><identifier>PMID: 31996408</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Age ; Bilingualism ; Birth weight ; Child, Preschool ; Children ; Children & youth ; Cohort analysis ; Cohort Studies ; Country of birth ; Education ; Educational Status ; Europe ; Families & family life ; Female ; Gestational Age ; Humans ; Infant, Extremely Premature ; Infant, Newborn ; Language ; Language Development ; Language policy ; Life Sciences ; Male ; Medical prognosis ; Medicin och hälsovetenskap ; Mothers - psychology ; Multiple births ; Neonates ; Parent educational background ; Population ; Population studies ; Population Surveillance ; Population-based studies ; Pregnancy ; Premature birth ; Questionnaires ; Santé publique et épidémiologie ; Sociodemographics ; Socioeconomic Factors ; Socioeconomics</subject><ispartof>Journal of epidemiology and community health (1979), 2020-04, Vol.74 (4), p.346-353</ispartof><rights>Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2020 Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b557t-1c4a0876705063adc23d69d6cb5c5e76334c74ad9be965e72330cab324fc91a33</citedby><cites>FETCH-LOGICAL-b557t-1c4a0876705063adc23d69d6cb5c5e76334c74ad9be965e72330cab324fc91a33</cites><orcidid>0000-0002-3284-6874 ; 0000-0001-5234-6474 ; 0000-0001-5615-0639 ; 0000-0002-9568-2969 ; 0000-0002-2156-154X ; 0000-0002-6972-3608 ; 0000-0002-0650-3173 ; 0000-0001-8963-7881</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,781,785,886,27926,27927</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31996408$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://inserm.hal.science/inserm-02504009$$DView record in HAL$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:144622102$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Sentenac, Mariane</creatorcontrib><creatorcontrib>Johnson, Samantha</creatorcontrib><creatorcontrib>Charkaluk, Marie-Laure</creatorcontrib><creatorcontrib>Sëppanen, Anna-Veera</creatorcontrib><creatorcontrib>Aden, Ulrika</creatorcontrib><creatorcontrib>Cuttini, Marina</creatorcontrib><creatorcontrib>Maier, Rolf</creatorcontrib><creatorcontrib>Mannamaa, Mairi</creatorcontrib><creatorcontrib>Zeitlin, Jennifer</creatorcontrib><creatorcontrib>the EPICE group</creatorcontrib><title>Maternal education and language development at 2 years corrected age in children born very preterm: results from a European population-based cohort study</title><title>Journal of epidemiology and community health (1979)</title><addtitle>J Epidemiol Community Health</addtitle><description>BackgroundSocioeconomic factors influence language development in the general population, but the association remains poorly documented in children born very preterm (VPT). We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal risk.MethodsData were from the Effective Perinatal Intensive Care in Europe (EPICE) population-based cohort of children born <32 weeks’ gestational age (GA) in 2011/2012. Regions from six countries (Estonia, France, Germany, Italy, Sweden and UK) used a validated short form MacArthur Developmental Communicative Inventories Checklist to assess language at 2 years corrected age. Perinatal variables were collected from clinical records. We assessed expressive language delay (ELD), defined as (a) not combining words; and (b) expressive vocabulary <10th percentile of norms for age and sex. Perinatal risk (low, moderate and high) was determined using GA, small for GA and neonatal morbidities. We estimated adjusted risk ratios (aRR) of ELD by maternal education with inverse weighting to account for non-response bias.ResultsOf 2741 children, 24.6% were not combining words and 39.7% had a low expressive vocabulary. Low maternal education (lower secondary or less compared with a bachelor’s degree or more) increased risks of ELD: not combining words: aRR=1.52 (95% CI 1.36 to 1.69); low expressive vocabulary: aRR=1.25 (1.04 to 1.51). For children with low perinatal risk, the aRR were 1.88 (1.26 to 2.80) and 1.44 (1.06 to 1.95), respectively, compared with those with high perinatal risks: 1.36 (1.10 to 1.67) and 1.11 (0.97 to 1.27), respectively.ConclusionLow maternal education affects ELD for children born VPT, although the association appears attenuated among those with highest perinatal risk.</description><subject>Age</subject><subject>Bilingualism</subject><subject>Birth weight</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Children & youth</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Country of birth</subject><subject>Education</subject><subject>Educational Status</subject><subject>Europe</subject><subject>Families & family life</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Humans</subject><subject>Infant, Extremely Premature</subject><subject>Infant, Newborn</subject><subject>Language</subject><subject>Language Development</subject><subject>Language policy</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Medicin och hälsovetenskap</subject><subject>Mothers - psychology</subject><subject>Multiple births</subject><subject>Neonates</subject><subject>Parent educational background</subject><subject>Population</subject><subject>Population studies</subject><subject>Population Surveillance</subject><subject>Population-based studies</subject><subject>Pregnancy</subject><subject>Premature birth</subject><subject>Questionnaires</subject><subject>Santé publique et épidémiologie</subject><subject>Sociodemographics</subject><subject>Socioeconomic Factors</subject><subject>Socioeconomics</subject><issn>0143-005X</issn><issn>1470-2738</issn><issn>1470-2738</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkk9rFDEYxgdRbK3ePUnAi6Cj-TfJprdSqhVWvCh4C5nk3e6sM5Mxf1b2o_htzTjbioJ4ykv4_Z6E5KmqpwS_JoSJNzuw25piompKWCP4veqUcIlrKtnqfnWKCWc1xs2Xk-pRjDtcRknVw-qEEaUEx6vT6scHkyCMpkfgsjWp8yMyo0O9GW-yuQHkYA-9nwYYEzIJUXQAEyKyPgSwCRyaoW5Edtv1LsCIWh9GtIdwQFOAkj2cowAx9ymiTfADMugqBz-BGdHkp9z_OrNuTSxZ1m99SCim7A6Pqwcb00d4clzPqs9vrz5dXtfrj-_eX16s67ZpZKqJ5QavpJC4wYIZZylzQjlh28Y2IAVj3EpunGpBibJBGcPWtIzyjVXEMHZW1Utu_A5TbvUUusGEg_am08etr2UCzSVThBZe_ZOfgne_pVuRcC4oJXh2Xy3u1vR_iNcXa92NsbyWxrTBHGO1JwV_seAl91uGmPTQRQt9-RzwOWrK-EoqpYgs6PO_0J3P87_OlGxEg5mcKbxQNvgYA2zuLkGwnhul50bpuVF6aVRRnh2DczuAuxNuK1SAlwvQDrv_x_0E5dzXeg</recordid><startdate>20200401</startdate><enddate>20200401</enddate><creator>Sentenac, Mariane</creator><creator>Johnson, Samantha</creator><creator>Charkaluk, Marie-Laure</creator><creator>Sëppanen, Anna-Veera</creator><creator>Aden, Ulrika</creator><creator>Cuttini, Marina</creator><creator>Maier, Rolf</creator><creator>Mannamaa, Mairi</creator><creator>Zeitlin, Jennifer</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><scope>ADTPV</scope><scope>AOWAS</scope><orcidid>https://orcid.org/0000-0002-3284-6874</orcidid><orcidid>https://orcid.org/0000-0001-5234-6474</orcidid><orcidid>https://orcid.org/0000-0001-5615-0639</orcidid><orcidid>https://orcid.org/0000-0002-9568-2969</orcidid><orcidid>https://orcid.org/0000-0002-2156-154X</orcidid><orcidid>https://orcid.org/0000-0002-6972-3608</orcidid><orcidid>https://orcid.org/0000-0002-0650-3173</orcidid><orcidid>https://orcid.org/0000-0001-8963-7881</orcidid></search><sort><creationdate>20200401</creationdate><title>Maternal education and language development at 2 years corrected age in children born very preterm: results from a European population-based cohort study</title><author>Sentenac, Mariane ; Johnson, Samantha ; Charkaluk, Marie-Laure ; Sëppanen, Anna-Veera ; Aden, Ulrika ; Cuttini, Marina ; Maier, Rolf ; Mannamaa, Mairi ; Zeitlin, Jennifer</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b557t-1c4a0876705063adc23d69d6cb5c5e76334c74ad9be965e72330cab324fc91a33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Age</topic><topic>Bilingualism</topic><topic>Birth weight</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Children & youth</topic><topic>Cohort analysis</topic><topic>Cohort Studies</topic><topic>Country of birth</topic><topic>Education</topic><topic>Educational Status</topic><topic>Europe</topic><topic>Families & family life</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Humans</topic><topic>Infant, Extremely Premature</topic><topic>Infant, Newborn</topic><topic>Language</topic><topic>Language Development</topic><topic>Language policy</topic><topic>Life Sciences</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Medicin och hälsovetenskap</topic><topic>Mothers - psychology</topic><topic>Multiple births</topic><topic>Neonates</topic><topic>Parent educational background</topic><topic>Population</topic><topic>Population studies</topic><topic>Population Surveillance</topic><topic>Population-based studies</topic><topic>Pregnancy</topic><topic>Premature birth</topic><topic>Questionnaires</topic><topic>Santé publique et épidémiologie</topic><topic>Sociodemographics</topic><topic>Socioeconomic Factors</topic><topic>Socioeconomics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sentenac, Mariane</creatorcontrib><creatorcontrib>Johnson, Samantha</creatorcontrib><creatorcontrib>Charkaluk, Marie-Laure</creatorcontrib><creatorcontrib>Sëppanen, Anna-Veera</creatorcontrib><creatorcontrib>Aden, Ulrika</creatorcontrib><creatorcontrib>Cuttini, Marina</creatorcontrib><creatorcontrib>Maier, Rolf</creatorcontrib><creatorcontrib>Mannamaa, Mairi</creatorcontrib><creatorcontrib>Zeitlin, Jennifer</creatorcontrib><creatorcontrib>the EPICE group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><collection>SwePub</collection><collection>SwePub Articles</collection><jtitle>Journal of epidemiology and community health (1979)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sentenac, Mariane</au><au>Johnson, Samantha</au><au>Charkaluk, Marie-Laure</au><au>Sëppanen, Anna-Veera</au><au>Aden, Ulrika</au><au>Cuttini, Marina</au><au>Maier, Rolf</au><au>Mannamaa, Mairi</au><au>Zeitlin, Jennifer</au><aucorp>the EPICE group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Maternal education and language development at 2 years corrected age in children born very preterm: results from a European population-based cohort study</atitle><jtitle>Journal of epidemiology and community health (1979)</jtitle><addtitle>J Epidemiol Community Health</addtitle><date>2020-04-01</date><risdate>2020</risdate><volume>74</volume><issue>4</issue><spage>346</spage><epage>353</epage><pages>346-353</pages><issn>0143-005X</issn><issn>1470-2738</issn><eissn>1470-2738</eissn><abstract>BackgroundSocioeconomic factors influence language development in the general population, but the association remains poorly documented in children born very preterm (VPT). We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal risk.MethodsData were from the Effective Perinatal Intensive Care in Europe (EPICE) population-based cohort of children born <32 weeks’ gestational age (GA) in 2011/2012. Regions from six countries (Estonia, France, Germany, Italy, Sweden and UK) used a validated short form MacArthur Developmental Communicative Inventories Checklist to assess language at 2 years corrected age. Perinatal variables were collected from clinical records. We assessed expressive language delay (ELD), defined as (a) not combining words; and (b) expressive vocabulary <10th percentile of norms for age and sex. Perinatal risk (low, moderate and high) was determined using GA, small for GA and neonatal morbidities. We estimated adjusted risk ratios (aRR) of ELD by maternal education with inverse weighting to account for non-response bias.ResultsOf 2741 children, 24.6% were not combining words and 39.7% had a low expressive vocabulary. Low maternal education (lower secondary or less compared with a bachelor’s degree or more) increased risks of ELD: not combining words: aRR=1.52 (95% CI 1.36 to 1.69); low expressive vocabulary: aRR=1.25 (1.04 to 1.51). For children with low perinatal risk, the aRR were 1.88 (1.26 to 2.80) and 1.44 (1.06 to 1.95), respectively, compared with those with high perinatal risks: 1.36 (1.10 to 1.67) and 1.11 (0.97 to 1.27), respectively.ConclusionLow maternal education affects ELD for children born VPT, although the association appears attenuated among those with highest perinatal risk.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>31996408</pmid><doi>10.1136/jech-2019-213564</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-3284-6874</orcidid><orcidid>https://orcid.org/0000-0001-5234-6474</orcidid><orcidid>https://orcid.org/0000-0001-5615-0639</orcidid><orcidid>https://orcid.org/0000-0002-9568-2969</orcidid><orcidid>https://orcid.org/0000-0002-2156-154X</orcidid><orcidid>https://orcid.org/0000-0002-6972-3608</orcidid><orcidid>https://orcid.org/0000-0002-0650-3173</orcidid><orcidid>https://orcid.org/0000-0001-8963-7881</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Age Bilingualism Birth weight Child, Preschool Children Children & youth Cohort analysis Cohort Studies Country of birth Education Educational Status Europe Families & family life Female Gestational Age Humans Infant, Extremely Premature Infant, Newborn Language Language Development Language policy Life Sciences Male Medical prognosis Medicin och hälsovetenskap Mothers - psychology Multiple births Neonates Parent educational background Population Population studies Population Surveillance Population-based studies Pregnancy Premature birth Questionnaires Santé publique et épidémiologie Sociodemographics Socioeconomic Factors Socioeconomics |
title | Maternal education and language development at 2 years corrected age in children born very preterm: results from a European population-based cohort study |
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