Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality

This registry study examined the association between aspirin use and hepatocellular carcinoma and liver-related mortality in adults in Sweden with hepatitis B or hepatitis C. The 10-year cumulative incidences of hepatocellular carcinoma and liver-related death were lower among aspirin users than amo...

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Veröffentlicht in:	The New England journal of medicine 2020-03, Vol.382 (11), p.1018-1028
Hauptverfasser:	Simon, Tracey G, Duberg, Ann-Sofi, Aleman, Soo, Chung, Raymond T, Chan, Andrew T, Ludvigsson, Jonas F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Aspirin Aspirin - administration & dosage Aspirin - adverse effects Bleeding Carcinoma, Hepatocellular - mortality Chronic infection Drug dosages Emigration Female Gastrointestinal Hemorrhage - chemically induced Hepatitis Hepatitis B Hepatitis B, Chronic - complications Hepatitis C Hepatitis C, Chronic - complications Hepatocellular carcinoma Humans Infections Liver cancer Liver diseases Liver Neoplasms - mortality Long-term effects Male Middle Aged Mortality Patients Prescriptions Prevention Registries Risk Sweden - epidemiology
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Beschreibung
Zusammenfassung:	This registry study examined the association between aspirin use and hepatocellular carcinoma and liver-related mortality in adults in Sweden with hepatitis B or hepatitis C. The 10-year cumulative incidences of hepatocellular carcinoma and liver-related death were lower among aspirin users than among nonusers.
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa1912035