Trial of Dexamethasone for Chronic Subdural Hematoma
In a trial that compared a 2-week course of dexamethasone with placebo in patients with a chronic subdural hematoma, a favorable outcome on the modified Rankin scale at 6 months was more common in the placebo group than in the dexamethasone group, but repeat surgery to evacuate a hematoma was perfor...
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| Veröffentlicht in: | The New England journal of medicine 2020-12, Vol.383 (27), p.2616-2627 |
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| container_title | The New England journal of medicine |
| container_volume | 383 |
| creator | Hutchinson, Peter J Edlmann, Ellie Bulters, Diederik Zolnourian, Ardalan Holton, Patrick Suttner, Nigel Agyemang, Kevin Thomson, Simon Anderson, Ian A Al-Tamimi, Yahia Z Henderson, Duncan Whitfield, Peter C Gherle, Monica Brennan, Paul M Allison, Annabel Thelin, Eric P Tarantino, Silvia Pantaleo, Beatrice Caldwell, Karen Davis-Wilkie, Carol Mee, Harry Warburton, Elizabeth A Barton, Garry Chari, Aswin Marcus, Hani J King, Andrew T Belli, Antonio Myint, Phyo K Wilkinson, Ian Santarius, Thomas Turner, Carole Bond, Simon Kolias, Angelos G |
| description | In a trial that compared a 2-week course of dexamethasone with placebo in patients with a chronic subdural hematoma, a favorable outcome on the modified Rankin scale at 6 months was more common in the placebo group than in the dexamethasone group, but repeat surgery to evacuate a hematoma was performed more frequently in the placebo group. |
| doi_str_mv | 10.1056/NEJMoa2020473 |
| format | Article |
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| subjects | Activities of daily living Administration, Oral Aged Blood Brain Clinical trials Combined Modality Therapy Consent Dexamethasone Dexamethasone - administration & dosage Dexamethasone - adverse effects Dexamethasone - therapeutic use Disabled Persons Dura mater Enrollments Female Glucocorticoids - administration & dosage Glucocorticoids - adverse effects Glucocorticoids - therapeutic use Hematoma Hematoma, Subdural, Chronic - complications Hematoma, Subdural, Chronic - drug therapy Hematoma, Subdural, Chronic - mortality Hematoma, Subdural, Chronic - surgery Humans Intention to Treat Analysis Male Meninges Middle Aged Patients Questionnaires Reoperation - statistics & numerical data Severity of Illness Index Steroids Surgery Treatment Outcome |
| title | Trial of Dexamethasone for Chronic Subdural Hematoma |
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