Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects

It is currently unclear whether plasma biomarkers can be used as independent prognostic tools to predict changes associated with early Alzheimer's disease. In this study, we sought to address this question by assessing whether plasma biomarkers can predict changes in amyloid load, tau accumulat...

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Veröffentlicht in:	BRAIN 2021-10, Vol.144 (9), p.2826-2836
Hauptverfasser:	Pereira, Joana B, Janelidze, Shorena, Stomrud, Erik, Palmqvist, Sebastian, van Westen, Danielle, Dage, Jeffrey L, Mattsson-Carlgren, Niklas, Hansson, Oskar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - blood Adult Aged Aged, 80 and over Amyloid beta-Peptides - blood amyloid-β Atrophy - blood Basic Medicine Biomarkers - blood Brain - diagnostic imaging Brain - metabolism cognition Cohort Studies Female Humans Longitudinal Studies Male Medical and Health Sciences Medicin och hälsovetenskap Medicinska och farmaceutiska grundvetenskaper Middle Aged MRI Neuropsychological Tests Neurosciences Neurovetenskaper Original Peptide Fragments - blood PET plasma biomarkers Predictive Value of Tests tau PET
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