Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis: a retrospective study of a male fertility preservation cohort

Abstract STUDY QUESTION What is the impact of cancer or hematological disorders on germ cells in pediatric male patients? SUMMARY ANSWER Spermatogonial quantity is reduced in testes of prepubertal boys diagnosed with cancer or severe hematological disorder compared to healthy controls and this reduc...

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Veröffentlicht in:	Human reproduction (Oxford) 2023-03, Vol.38 (3), p.359-370
Hauptverfasser:	Masliukaite, Ieva, Ntemou, Elissavet, Feijen, Elizabeth A M, van de Wetering, Marianne, Meissner, Andreas, Soufan, Alexandre T, Repping, Sjoerd, Kremer, Leontien M C, Jahnukainen, Kirsi, Goossens, Ellen, van Pelt, Ans M M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Child Cryopreservation Fertility Preservation - methods Hematologic Diseases Humans Hydroxyurea Male Medicin och hälsovetenskap Neoplasms Original Retrospective Studies Spermatogonia Testis
Online-Zugang:	Volltext
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