Cystatin C–Based Equation to Estimate GFR without the Inclusion of Race and Sex

Estimating equations for the glomerular filtration rate — EKFC eGFRcr (creatinine) and EKFC eGFRcys (cystatin C) — were tested. EKFC eGFRcys was unbiased and accurate, irrespective of the inclusion of race or sex.

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Veröffentlicht in:	The New England journal of medicine 2023-01, Vol.388 (4), p.333-343
Hauptverfasser:	Pottel, Hans, Björk, Jonas, Rule, Andrew D., Ebert, Natalie, Eriksen, Björn O., Dubourg, Laurence, Vidal-Petiot, Emmanuelle, Grubb, Anders, Hansson, Magnus, Lamb, Edmund J., Littmann, Karin, Mariat, Christophe, Melsom, Toralf, Schaeffner, Elke, Sundin, Per-Ola, Åkesson, Anna, Larsson, Anders, Cavalier, Etienne, Bukabau, Justine B., Sumaili, Ernest K., Yayo, Eric, Monnet, Dagui, Flamant, Martin, Nyman, Ulf, Delanaye, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Adult Africa Africa - epidemiology Age Biomarkers Biomarkers - blood Black or African American Black People Black People - statistics & numerical data Chronic Kidney Disease Clinical Medicine Clinical Medicine General Creatinine Creatinine - blood Cystatin C Cystatin C - blood cystatin C, creatinine, GFR Epidemiology Europe Europe - epidemiology Female General Medicine Glomerular Filtration Rate Glomerular Filtration Rate - physiology Human health sciences Humans Infant Kidney diseases Kidney Replacement Therapy Kidney Transplantation Kidney transplants Klinisk medicin Laboratory medicine & medical technology Life Sciences Male Medical and Health Sciences Medicin och hälsovetenskap Middle Aged Médecine de laboratoire & technologie médicale Nephrology Nephrology General Patients Race Factors Renal Insufficiency, Chronic Renal Insufficiency, Chronic - blood Renal Insufficiency, Chronic - epidemiology Renal Insufficiency, Chronic - ethnology Reproducibility of Results Scaling Sciences de la santé humaine Sex Sex Factors Sweden Sweden - epidemiology United States United States - epidemiology Urologi och njurmedicin Urologie & néphrologie Urology & nephrology Urology and Nephrology Values White People White People - statistics & numerical data
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Beschreibung
Zusammenfassung:	Estimating equations for the glomerular filtration rate — EKFC eGFRcr (creatinine) and EKFC eGFRcys (cystatin C) — were tested. EKFC eGFRcys was unbiased and accurate, irrespective of the inclusion of race or sex.
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa2203769