Benefit of converting enzyme inhibition on left ventricular volumes and ejection fraction in patients receiving β-blockade after myocardial infarction

Benefit of converting enzyme inhibition on left ventricular volumes and ejection fraction in patients receiving β-blockade after myocardial infarction

β-blockers reduce infarct size and improve survival after acute myocardial infarction (MI). Post-MI angiotensin-converting enzyme inhibition also improves survival and may attenuate left ventricular (LV) dilatation. We evaluated the effect of early enalapril treatment on LV volumes and ejection frac...

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Veröffentlicht in:The American heart journal 1996, Vol.132 (1), p.71-77
Hauptverfasser: Bonarjee, Vernon V.S., Carstensen, Steen, Caidahl, Kenneth, Nilsen, Dennis W.T., Edner, Magnus, Lindvall, Kaj, Snapinn, Steven M., Berning, Jens
Format: Artikel
Sprache:eng
Schlagworte:
Antianginal agents. Coronary vasodilator agents
Biological and medical sciences
Cardiovascular system
Medical sciences
Pharmacology. Drug treatments
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Zusammenfassung:β-blockers reduce infarct size and improve survival after acute myocardial infarction (MI). Post-MI angiotensin-converting enzyme inhibition also improves survival and may attenuate left ventricular (LV) dilatation. We evaluated the effect of early enalapril treatment on LV volumes and ejection fraction (EF) in patients on concomitant β-blockade after MI. Intravenous enalaprilat or placebo was administered
ISSN:0002-8703
1097-6744
DOI:10.1016/S0002-8703(96)90392-0