Long-term dental development in children after treatment for malignant disease

A radiographic dental examination was performed in 16 children conditioned with total body irradiation (TBI) and cyclophosphamide (CY) prior to bone marrow transplantation (BMT), and in 52 children treated with multiagent chemotherapy. For each child, three age- and sex-matched healthy controls were...

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Veröffentlicht in:	European journal of orthodontics 1997-04, Vol.19 (2), p.151-159
Hauptverfasser:	Näsman, Margareta, Forsberg, Carl-Magnus, Dahllöf, Göran
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Antineoplastic Agents, Alkylating - therapeutic use Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bicuspid - drug effects Bicuspid - pathology Bicuspid - radiation effects Bone Marrow Transplantation Case-Control Studies Child Cuspid - drug effects Cuspid - pathology Cuspid - radiation effects Cyclophosphamide - therapeutic use Female Hematologic Neoplasms - drug therapy Hematologic Neoplasms - radiotherapy Humans Incisor - diagnostic imaging Incisor - drug effects Incisor - pathology Male Mandible Medicin och hälsovetenskap Molar - drug effects Molar - pathology Molar - radiation effects Neoplasms - drug therapy Neoplasms - radiotherapy Neoplasms - therapy Odontogenesis - drug effects Odontogenesis - radiation effects Odontometry Radiography, Panoramic Tooth Crown - diagnostic imaging Tooth Crown - drug effects Tooth Crown - pathology Tooth Root - drug effects Tooth Root - pathology Tooth Root - radiation effects Whole-Body Irradiation
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Zusammenfassung:	A radiographic dental examination was performed in 16 children conditioned with total body irradiation (TBI) and cyclophosphamide (CY) prior to bone marrow transplantation (BMT), and in 52 children treated with multiagent chemotherapy. For each child, three age- and sex-matched healthy controls were selected. Evaluation of disturbances in dental development and tooth size was based on planimetric measurements of mandibular teeth on panoramic radiographs. Short V-shaped roots were diagnosed in 94 per cent of the children treated with TBI/CY compared with 19 per cent in the chemotherapy group (P
ISSN:	0141-5387 1460-2210
DOI:	10.1093/ejo/19.2.151