Four-year data after pediatric renal transplantation: A randomized trial of tacrolimus vs. cyclosporin microemulsion

: This study was undertaken to compare the efficacy and safety of tacrolimus (Tac) with cyclosporin microemulsion (CyA) in pediatric renal recipients. A 6‐month, randomized, prospective, open, parallel group study with an open extension phase was conducted in 18 centers from nine European countries...

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Veröffentlicht in:	Pediatric transplantation 2005-08, Vol.9 (4), p.498-503
Hauptverfasser:	Filler, Guido, Webb, Nicholas J. A., Milford, David V., Watson, Alan R., Gellermann, Jutta, Tyden, Gunnar, Grenda, Ryszard, Vondrak, Karel, Hughes, David, Offner, Gisela, Griebel, Martin, Brekke, Inge B., McGraw, Mary, Balzar, Egon, Friman, Styrbjörn, Trompeter, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenal Cortex Hormones - therapeutic use Azathioprine - therapeutic use Biological and medical sciences Child cyclosporin microemulsion Cyclosporine - therapeutic use Emulsions Europe Female Glomerular Filtration Rate Graft Rejection - epidemiology Graft Rejection - prevention & control Graft Rejection/epidemiology/prevention & control Graft Survival Humans Immunosuppressive Agents - therapeutic use Incidence Kidney Function Tests Kidney Transplantation Male Medical and Health Sciences Medical sciences Medicin och hälsovetenskap pediatric Prospective Studies renal transplant Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system surrogate marker tacrolimus Tacrolimus - therapeutic use
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Beschreibung
Zusammenfassung:	: This study was undertaken to compare the efficacy and safety of tacrolimus (Tac) with cyclosporin microemulsion (CyA) in pediatric renal recipients. A 6‐month, randomized, prospective, open, parallel group study with an open extension phase was conducted in 18 centers from nine European countries. In total, 196 pediatric patients (
ISSN:	1397-3142 1399-3046
DOI:	10.1111/j.1399-3046.2005.00334.x