Visual function and quality of life in children and adolescents with anophthalmia and microphthalmia treated with ocular prosthesis

Purpose To evaluate health‐related quality of life (HR‐QoL), vision‐related (VR‐)QoL and perceptual visual dysfunction (PVD) among individuals with anophthalmia (A) and microphthalmia (M) treated with ocular prosthesis. Methods The study comprised 15 individuals (mean age 6.6 years; range 1.7–14.1) with unilateral A or M. Three validated instruments measuring HR‐QoL and VR‐QoL were used: The Pediatric QoL Inventory (PedsQL), consisting of physical and psychosocial self‐report and parent‐proxy report (2–18 years); Children’s Visual Function Questionnaire (CVFQ); and Effects of Youngsters’ Eyesight on Quality of Life (EYE‐Q). Perceptual visual dysfunctions (PVDs) were assessed by history taking according to a specific protocol. Results A/M children and their parents showed low HR‐QoL scores (PedsQL total score: 66.3; 69.6) compared with controls (83.0; 87.61) (p = 0.0035 and