Sodium Oxybate for Alcohol Dependence: A Network Meta-Regression Analysis Considering Population Severity at Baseline and Treatment Duration

Abstract Aims The estimated effect of sodium oxybate (SMO) in the treatment of alcohol dependence is heterogeneous. Population severity and treatment duration have been identified as potential effect modifiers. Population severity distinguishes heavy drinking patients with

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Veröffentlicht in:	Alcohol and alcoholism (Oxford) 2023-03, Vol.58 (2), p.125-133
Hauptverfasser:	Guiraud, Julien, Addolorato, Giovanni, Aubin, Henri-Jean, Bachelot, Sylvie, Batel, Philippe, de Bejczy, Andrea, Benyamina, Amine, Caputo, Fabio, Couderc, Monique, Dematteis, Maurice, Goudriaan, Anna E, Gual, Antoni, Lecoustey, Sylvie, Lesch, Otto-Michael, Maremmani, Icro, Nutt, David J, Paille, François, Perney, Pascal, Rehm, Jürgen, Rolland, Benjamin, Scherrer, Bruno, Simon, Nicolas, Söderpalm, Bo, Somaini, Lorenzo, Sommer, Wolfgang H, Spanagel, Rainer, Walter, Henriette, van den Brink, Wim
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism - complications Duration of Therapy Ethanol Humans Life Sciences Psychiatry Psykiatri Regression Analysis Sodium Oxybate - adverse effects Treatment Outcome
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Zusammenfassung:	Abstract Aims The estimated effect of sodium oxybate (SMO) in the treatment of alcohol dependence is heterogeneous. Population severity and treatment duration have been identified as potential effect modifiers. Population severity distinguishes heavy drinking patients with
ISSN:	0735-0414 1464-3502 1464-3502
DOI:	10.1093/alcalc/agac070