Persisting prediabetic conditions and glomerular filtration rate – A longitudinal study

The aim was to explore differences in the development of eGFR in persisting prediabetic conditions. This prospective study including 1327 individuals showed that eGFR decreased more in individuals with persisting IGT than in individuals with persisting IFG. Repeating OGTT and monitoring eGFR might i...

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Veröffentlicht in:	Primary care diabetes 2022-08, Vol.16 (4), p.597-599
Hauptverfasser:	Diurlin, Sven, Lindblad, Ulf, Daka, Bledar, Hellgren, Margareta I
Format:	Artikel
Sprache:	eng
Schlagworte:	Allmän medicin beta-cell function Endocrinology & Metabolism Endocrinology and Diabetes Endokrinologi och diabetes Family Medicine General & Internal Medicine Impaired fasting glucose Impaired glucose tolerance insulin-resistance Kidney function Prevention Primary health care
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Zusammenfassung:	The aim was to explore differences in the development of eGFR in persisting prediabetic conditions. This prospective study including 1327 individuals showed that eGFR decreased more in individuals with persisting IGT than in individuals with persisting IFG. Repeating OGTT and monitoring eGFR might improve the risk estimation in prediabetes. •Different kinds of persisting prediabetes differ in renal impairment over 10 years.•Persisting IGT seems worse than persisting IFG, considering eGFR decline.•Persisting IGT resembles type 2 diabetes, considering eGFR decline over 10 years.•Repeating OGTT and monitoring eGFR might improve risk estimation in prediabetes.
ISSN:	1751-9918 1878-0210 1878-0210
DOI:	10.1016/j.pcd.2022.05.013