Myocardial, renal and intestinal injury in liver resection surgery—A prospective observational pilot study

Background Post‐operative organ complications in liver resection surgery are not uncommon. This prospective observational pilot study was performed to evaluate the incidence, degree and timing of myocardial, renal and intestinal injury in patients undergoing liver resection surgery using the low central venous pressure (LCVP) technique and the Pringle manoeuvre. Methods Blood samples were obtained before, during and after elective liver resection until post‐operative day (POD) 5. High‐sensitive troponin T (hs‐TnT), serum creatinine, urea, intestinal fatty acid binding protein (I‐FABP), D‐lactate, arterial lactate, portal lactate, amylase, as well as urine N‐acetyl‐ß‐D‐glucosaminidase (NAG) were analysed. Systemic haemodynamics were measured intraoperatively. Results Eighteen patients fulfilled the protocol. The Pringle manoeuvre was used in all but 1 patient. hs‐TnT increased significantly over time (P