Predictive value of preoperative neutrophil-to-lymphocyte ratio on the prognosis of germ cell testicular tumors

We investigated the prognostic value of preoperative neutrophil-to-lymphocyte ratio (NLR) on germ cell testicular tumors (GCT). The data of 53 patients who underwent inguinal orchiectomy were analyzed retrospectively. NLR was calculated from the preoperative complete blood cell counts. Receiver oper...

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Veröffentlicht in:Turkish journal of urology 2017-03, Vol.43 (1), p.55-61
Hauptverfasser: Bolat, Deniz, Aydoğdu, Özgü, Polat, Salih, Yarımoğlu, Serkan, Bozkurt, İbrahim Halil, Yonguç, Tarık, Şen, Volkan
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Sprache:eng
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Zusammenfassung:We investigated the prognostic value of preoperative neutrophil-to-lymphocyte ratio (NLR) on germ cell testicular tumors (GCT). The data of 53 patients who underwent inguinal orchiectomy were analyzed retrospectively. NLR was calculated from the preoperative complete blood cell counts. Receiver operating characteristic (ROC) analysis was performed to find the threshold values for NLR. Correlations between cancer-specific survival (CSS) and progression-free survival (PFS) and NLR were evaluated. The mean follow-up time was 23.55±18.06 months. The mean level of NLR was 3.08±1.81. Optimal threshold values of NLR was calculated as 3.55 for PFS (area under curve, AUC: 0.55) and 3.0 for CSS (AUC: 0.66). For patients with a NLR of
ISSN:2149-3235
2149-3057
2980-1478
DOI:10.5152/tud.2016.38924