Effects of long-term restricted feeding on plasma leptin, hepatic leptin expression and leptin receptor expression in juvenile Atlantic salmon ( Salmo salar L.)

Highlights ► Feed-restriction increases leptin-a1 gene expression and plasma leptin in Atlantic salmon parr. ► The two leptin genes ( lepa1 and lepa2 ) appear to be differentially regulated. ► Leptin receptor gene expression in the brain is up-regulated during early summer. ► The two leptin genes ar...

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Veröffentlicht in:General and comparative endocrinology 2012-01, Vol.175 (1), p.92-99
Hauptverfasser: Trombley, Susanne, Maugars, Gersende, Kling, Peter, Björnsson, Björn Thrandur, Schmitz, Monika
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Sprache:eng
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Zusammenfassung:Highlights ► Feed-restriction increases leptin-a1 gene expression and plasma leptin in Atlantic salmon parr. ► The two leptin genes ( lepa1 and lepa2 ) appear to be differentially regulated. ► Leptin receptor gene expression in the brain is up-regulated during early summer. ► The two leptin genes are almost exclusively expressed in the liver. ► Leptin receptor is expressed in the brain as well as in various peripheral tissues.
ISSN:0016-6480
1095-6840
1095-6840
DOI:10.1016/j.ygcen.2011.10.001