Endothelial cell antibody-mediated rejection and successful retransplantation in a heart transplanted patient

Antibody-mediated rejection (AMR) plays a significant role in cardiac allograft dysfunction, and recently a consensus regarding the diagnosis of AMR has been published. To our knowledge, it has not previously been reported that acute graft failure related to AMR, and antiendothelial cell antibodies...

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Veröffentlicht in:	European journal of cardio-thoracic surgery 2012-12, Vol.42 (6), p.1044-1046
Hauptverfasser:	Sigurdardottir, Vilborg, Kolsrud, Oscar, Hernandez, Nidia, Dellgren, Göran
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Biomarkers - metabolism Cardiology. Vascular system Clinical Medicine Endothelial Cells - immunology Graft Rejection - immunology Heart Failure - surgery Heart Transplantation - immunology Humans Immunoglobulin M - metabolism Klinisk medicin Male Medical sciences Pneumology Reoperation Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart
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Beschreibung
Zusammenfassung:	Antibody-mediated rejection (AMR) plays a significant role in cardiac allograft dysfunction, and recently a consensus regarding the diagnosis of AMR has been published. To our knowledge, it has not previously been reported that acute graft failure related to AMR, and antiendothelial cell antibodies can successfully be diagnosed to allow the patient to receive the outlined treatment and undergo a subsequent retransplantation.
ISSN:	1010-7940 1873-734X 1873-734X
DOI:	10.1093/ejcts/ezs368