Heart rate at baseline influences the effect of ivabradine on cardiovascular outcomes in chronic heart failure: analysis from the SHIFT study

Background We analysed the effect of ivabradine on outcomes in heart failure (HF) patients on recommended background therapies with heart rates ≥75 bpm and

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Veröffentlicht in:	Clinical research in cardiology 2013-01, Vol.102 (1), p.11-22
Hauptverfasser:	Böhm, Michael, Borer, Jeffrey, Ford, Ian, Gonzalez-Juanatey, Jose R., Komajda, Michel, Lopez-Sendon, Jose, Reil, Jan-Christian, Swedberg, Karl, Tavazzi, Luigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anti-Arrhythmia Agents - adverse effects Anti-Arrhythmia Agents - therapeutic use Benzazepines - adverse effects Benzazepines - therapeutic use Cardiology Cardiovascular outcomes Chronic Disease Clinical Medicine Disease Progression Double-Blind Method Female Heart failure Heart Failure - diagnosis Heart Failure - drug therapy Heart Failure - mortality Heart Failure - physiopathology Heart Rate Hospitalization Humans Ivabradine Kaplan-Meier Estimate Klinisk medicin Male Medicine Medicine & Public Health Middle Aged Original Paper Patient Selection Proportional Hazards Models Risk Assessment Risk Factors Systolic dysfunction Time Factors Treatment Outcome
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Beschreibung
Zusammenfassung:	Background We analysed the effect of ivabradine on outcomes in heart failure (HF) patients on recommended background therapies with heart rates ≥75 bpm and
ISSN:	1861-0684 1861-0692 1861-0692
DOI:	10.1007/s00392-012-0467-8