A population‐based intervention study on elevated serum levels of methylmalonic acid and total homocysteine in elderly people: results after 36 months of follow‐up

. Objectives. To study the effects of vitamin B12 and folic acid treatment on haematological measures, reported symptoms and clinical findings over a 3‐year period. Design. A longitudinal two‐cohort study. Setting. A mid‐Swedish community. Subjects. A 20% random sample of persons 70 years or old...

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Veröffentlicht in:	Journal of internal medicine 2004-11, Vol.256 (5), p.446-452
Hauptverfasser:	Björkegren, K., Svärdsudd, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Cohort Studies Comparative Study Female folate Folic Acid - therapeutic use Follow-Up Studies General aspects homocysteine Homocysteine - blood Humans Longitudinal Studies Male Medical sciences methylmalonic acid Methylmalonic Acid - blood symptoms treatment trial Vitamin B 12 - therapeutic use Vitamin B 12 Deficiency - drug therapy vitamin B12
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Zusammenfassung:	. Objectives. To study the effects of vitamin B12 and folic acid treatment on haematological measures, reported symptoms and clinical findings over a 3‐year period. Design. A longitudinal two‐cohort study. Setting. A mid‐Swedish community. Subjects. A 20% random sample of persons 70 years or older in a defined geographical area were invited to a survey (n = 266). Sixty‐nine persons who had serum cobalamin
ISSN:	0954-6820 1365-2796
DOI:	10.1111/j.1365-2796.2004.01393.x