Association of venous thromboembolism and clozapine

Association of venous thromboembolism and clozapine

Data from the Swedish Adverse Reactions Advisory Committee suggest that use of clozapine is associated with venous thromboembolic complications. We summarise 12 cases of thromboembolism during clozapine treatment. In five cases the outcome was fatal.

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Bibliographische Detailangaben
Veröffentlicht in:The Lancet (British edition) 2000-04, Vol.355 (9210), p.1155-1156
Hauptverfasser: Hägg, Staffan, Spigset, Olav, Söderström, Torbjörn G
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Adverse Drug Reaction Reporting Systems - statistics & numerical data
Antipsychotic Agents - adverse effects
Biological and medical sciences
Clozapine - adverse effects
Drug therapy
Drug toxicity and drugs side effects treatment
Female
Humans
Male
Medical research
Medical sciences
MEDICIN
MEDICINE
Middle Aged
Pharmacology. Drug treatments
Pulmonary Embolism - chemically induced
Sweden - epidemiology
Thromboembolism
Toxicity: blood
Venous Thrombosis - chemically induced
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Beschreibung
Zusammenfassung:Data from the Swedish Adverse Reactions Advisory Committee suggest that use of clozapine is associated with venous thromboembolic complications. We summarise 12 cases of thromboembolism during clozapine treatment. In five cases the outcome was fatal.
ISSN:0140-6736
1474-547X
1474-547X
DOI:10.1016/S0140-6736(00)02066-3