EANM enabling guide: how to improve the accessibility of clinical dosimetry

Dosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic concepts. However, the additional resource requirements are often seen as a barrier to implementation. This guide discusses the requirements for dosimetry...

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Veröffentlicht in:European journal of nuclear medicine and molecular imaging 2023-06, Vol.50 (7), p.1861-1868
Hauptverfasser: Gear, Jonathan, Stokke, Caroline, Terwinghe, Christelle, Gnesin, Silvano, Sandström, Mattias, Tran-Gia, Johannes, Cremonesi, Marta, Cicone, Francesco, Verburg, Fredrik, Hustinx, Roland, Giovanella, Luca, Herrmann, Ken, Gabiña, Pablo Minguez
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Sprache:eng
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Zusammenfassung:Dosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic concepts. However, the additional resource requirements are often seen as a barrier to implementation. This guide discusses the requirements for dosimetry and demonstrates how a dosimetry regimen can be tailored to the available facilities of a centre. The aim is to help centres wishing to initiate a dosimetry service but may not have the experience or resources of some of the more established therapy and dosimetry centres. The multidisciplinary approach and different personnel requirements are discussed and key equipment reviewed example protocols demonstrating these factors are given in the supplementary material for the main therapies carried out in nuclear medicine, including [ 131 I]-NaI for benign thyroid disorders, [ 177 Lu]-DOTATATE and 131 I-mIBG for neuroendocrine tumours and [ 90 Y]-microspheres for unresectable hepatic carcinoma.
ISSN:1619-7070
1619-7089
1619-7089
DOI:10.1007/s00259-023-06226-z