Daytime urotherapy in nocturnal enuresis: a randomised, controlled trial

ObjectiveAccording to international guidelines, children with enuresis are recommended urotherapy, or basic bladder advice, before treatment with evidence-based alternatives such as the enuresis alarm is given. The efficacy of this strategy has, however, not been supported by controlled studies. We wanted to test if basic bladder advice is useful in enuresis.DesignRandomised, controlled trial.SettingPaediatric outpatient ward, regional hospital.PatientsTreatment-naïve enuretic children aged ≥6 years, with no daytime incontinence.InterventionsThree groups, each during 8 weeks: (A) basic bladder advice—that is, voiding and drinking according to a strict schedule and instructions regarding toilet posture, (B) enuresis alarm therapy and (C) no treatment (control group).Main outcome measuresReduction in enuresis frequency during week 7–8 compared with baseline.ResultsThe median number of wet nights out of 14 before and at the end of treatment were in group A (n=20) 12.5 and 11.5 (p=0.44), in group B (n=22) 11.0 and 3.5 (p