Single-molecule X-ray diffraction

Single-molecule X-ray diffraction

Free-electron lasers could provide femtosecond X-ray flashes with a peak brilliance 10–11 orders of magnitude higher than that which is currently available from synchrotrons. Such pulses may allow structural studies of single biomolecules before radiation damage destroys them and may permit the imag...

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Veröffentlicht in:Current Opinion in Structural Biology 2000-10, Vol.10 (5), p.569-573
1. Verfasser: Hajdu, Janos
Format: Artikel
Sprache:eng
Schlagworte:
Lasers
Radiation Effects
X-Ray Diffraction - methods
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Zusammenfassung:Free-electron lasers could provide femtosecond X-ray flashes with a peak brilliance 10–11 orders of magnitude higher than that which is currently available from synchrotrons. Such pulses may allow structural studies of single biomolecules before radiation damage destroys them and may permit the imaging of complex structures without the need to amplify scattered radiation through Bragg reflections.
ISSN:0959-440X
1879-033X
DOI:10.1016/S0959-440X(00)00133-0