Intramolecular amidomercurations under allylic control: a stereoselective synthesis of (+)-pseudohygroline and (+)-3-hydroxypyrrolizidine
The diastereoselectivity of intramolecular amidomercurations can be reversed by altering the remote allylic substituent of ω-alkenylcarbamates. This methodology has been applied to the synthesis of (+)-pseudohygroline and (+)-3-hydroxypyrrolizidine. Graphic
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| Veröffentlicht in: | Tetrahedron: asymmetry 2001-03, Vol.12 (4), p.597-604 |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | The diastereoselectivity of intramolecular amidomercurations can be reversed by altering the remote allylic substituent of ω-alkenylcarbamates. This methodology has been applied to the synthesis of (+)-pseudohygroline and (+)-3-hydroxypyrrolizidine.
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| ISSN: | 0957-4166 1362-511X |
| DOI: | 10.1016/S0957-4166(01)00064-7 |