Stor enighet om att screening för bukaortaaneurysm räddar liv: Misleading study in The Lancet on the outcome of the Swedish AAA screening program

In a recent publication in The Lancet Johansson and colleagues claim no effect on aneurysm mortality among men participating in the Swedish AAA screening program, and question its justification. The study is, however, limited by a corrupt study design and incorrect data, making the publication misle...

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Veröffentlicht in:Läkartidningen 2018, Vol.115
1. Verfasser: Wanhainen, Anders
Format: Artikel
Sprache:swe
Online-Zugang:Volltext
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Zusammenfassung:In a recent publication in The Lancet Johansson and colleagues claim no effect on aneurysm mortality among men participating in the Swedish AAA screening program, and question its justification. The study is, however, limited by a corrupt study design and incorrect data, making the publication misleading. On the contrary, several RCTs and contemporary nationwide data with sufficient follow-up clearly show that AAA screening saves lives and is highly cost-effective. The program has so far identified about 6000 men with an AAA, of whom 1500 have been operated on to prevent rupture. Thus, more than 750 men have experienced a longer life (by a mean of 8 years) as a result of the program. Continuous evaluation of the program is important but requires a scientifically sound methodology. I en artikel i Lancet ifrågasätts nyttan av screening för bukaortaaneurysm. Studien är behäftad med allvarliga brister. Randomiserade studier visar att screening halverar dödligheten och är kostnadseffektiv, vilket bekräftats i en studie av det svenska screeningprogrammet.
ISSN:0023-7205
1652-7518