Characterization of the γ-aminobutyric acid signaling system in the zebrafish ( Danio rerio Hamilton) central nervous system by reverse transcription-quantitative polymerase chain reaction

Highlights • Zebrafish brains and retinas express the genes for GABA signaling. • The GABA system depicts regional brain differences. • The zebrafish GABA system shares similarities with that of mammals. • Zebrafish, as mammals, splice the γ2 subunit of the GABAA receptor. • The GABAA receptor α6a ,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2017-02, Vol.343, p.300-321
Hauptverfasser:	Cocco, Arianna, Carolina Rönnberg, A.M, Jin, Zhe, André, Gonçalo Igreja, Vossen, Laura E, Bhandage, Amol K, Thörnqvist, Per-Ove, Birnir, Bryndis, Winberg, Svante
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Brain - metabolism comparative neuroscience Fish Proteins - genetics Fish Proteins - metabolism GABA GABA Plasma Membrane Transport Proteins - genetics GABA Plasma Membrane Transport Proteins - metabolism gamma-Aminobutyric Acid - metabolism Gene Expression Neurology neurotransmitter systems Protein Isoforms receptors Receptors, GABA-A - genetics Receptors, GABA-A - metabolism Receptors, GABA-B - genetics Receptors, GABA-B - metabolism Retina - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Sequence Alignment Sequence Homology, Amino Acid teleost zebrafish Zebrafish - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Zebrafish brains and retinas express the genes for GABA signaling. • The GABA system depicts regional brain differences. • The zebrafish GABA system shares similarities with that of mammals. • Zebrafish, as mammals, splice the γ2 subunit of the GABAA receptor. • The GABAA receptor α6a , α6b genes are tissue-specifically expressed.
ISSN:	0306-4522 1873-7544 1873-7544
DOI:	10.1016/j.neuroscience.2016.07.018