Albuminuria and cardiovascular events in patients with acute coronary syndromes: Results from the TRACER trial

Albuminuria is associated with cardiovascular (CV) outcomes. We evaluated albuminuria, alone and in combination with estimated glomerular filtration rate (eGFR), as a predictor of mortality and CV morbidity in 12,944 patients with non–ST-segment elevation acute coronary syndromes. Baseline serum cre...

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Veröffentlicht in:	The American heart journal 2016-08, Vol.178, p.1-8
Hauptverfasser:	Åkerblom, Axel, Clare, Robert M., Lokhnygina, Yuliya, Wallentin, Lars, Held, Claes, Van de Werf, Frans, Moliterno, David J., Patel, Uptal D., Leonardi, Sergio, Armstrong, Paul W., Harrington, Robert A., White, Harvey D., Aylward, Philip E., Mahaffey, Kenneth W., Tricoci, Pierluigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - epidemiology Acute Coronary Syndrome - metabolism Acute Coronary Syndrome - therapy Acute coronary syndromes Acute Kidney Injury - epidemiology Aged Albuminuria - epidemiology Albuminuria - metabolism Biomarkers Blood Cardiovascular disease Cardiovascular Diseases - mortality Cause of Death Comorbidity Coronary vessels Creatinine - blood Diabetes Diabetes Mellitus - epidemiology Female Glomerular Filtration Rate Heart attacks Heart surgery Hemorrhage - epidemiology Humans Hypertension Hypertension - epidemiology Incidence Kaplan-Meier Estimate Kidney diseases Male Middle Aged Mortality Myocardial Infarction - epidemiology Prognosis Proportional Hazards Models Proteins Risk Assessment Risk Factors Stroke
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Zusammenfassung:	Albuminuria is associated with cardiovascular (CV) outcomes. We evaluated albuminuria, alone and in combination with estimated glomerular filtration rate (eGFR), as a predictor of mortality and CV morbidity in 12,944 patients with non–ST-segment elevation acute coronary syndromes. Baseline serum creatinine and urinary dipsticks were obtained, with albuminuria stratified into no/trace albuminuria, microalbuminuria (≥30 but
ISSN:	0002-8703 1097-6744 1097-6744
DOI:	10.1016/j.ahj.2016.04.013