Sex-dependent expression of anti-Müllerian hormone (amh) and amh receptor 2 during sex organ differentiation and characterization of the Müllerian duct development in Xenopus tropicalis

Highlights • Ontogenetic amh, amhr2 and progesterone receptor mRNA profiles were characterized. • amh and amhr2 mRNA levels showed sexually dimorphic developmental patterns. • The present study is the first to report amhr2 mRNA levels in amphibians. • The Müllerian ducts started to develop at the en...

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Veröffentlicht in:	General and comparative endocrinology 2016-04, Vol.229, p.132-144
Hauptverfasser:	Erika, Jansson, Anna, Mattsson, Jared, Goldstone, Cecilia, Berg
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Mullerian Hormone - metabolism Cell Differentiation Endocrinology & Metabolism Female Frogs Male Molecular sex marker Mullerian Ducts - embryology Müllerian inhibiting substance Receptors, Peptide Receptors, Transforming Growth Factor beta Reproductive organ development Sex differentiation Sex Differentiation - genetics Xenopus - metabolism
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Zusammenfassung:	Highlights • Ontogenetic amh, amhr2 and progesterone receptor mRNA profiles were characterized. • amh and amhr2 mRNA levels showed sexually dimorphic developmental patterns. • The present study is the first to report amhr2 mRNA levels in amphibians. • The Müllerian ducts started to develop at the end of the larval period. • amh mRNA is proposed as a testicular marker in Xenopus tropicalis tadpoles.
ISSN:	0016-6480 1095-6840 1095-6840
DOI:	10.1016/j.ygcen.2016.03.018