Comparison of Prognostic Scores for Patients with Colorectal Cancer Peritoneal Metastases Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Background There are three prognostic scores for the cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) treatment of colorectal cancer peritoneal metastases: the newly introduced COREP (colorectal peritoneal) score, the peritoneal surface disease severity score (PSDS),...

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Veröffentlicht in:Annals of surgical oncology 2013-12, Vol.20 (13), p.4183-4189
Hauptverfasser: Cashin, Peter H., Graf, Wilhelm, Nygren, Peter, Mahteme, Haile
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Sprache:eng
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Zusammenfassung:Background There are three prognostic scores for the cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) treatment of colorectal cancer peritoneal metastases: the newly introduced COREP (colorectal peritoneal) score, the peritoneal surface disease severity score (PSDS), and the prognostic score (PS). The aim was to determine which prognostic score had the best prognostic value. Methods Between 2006 and 2010, a total of 77 patients with peritoneal metastases from colorectal cancer underwent CRS/HIPEC treatment. The COREP, PSDS, and PS scores were successfully applied to 56 patients (73 %) having sufficient data. The end points were prediction of open-and-close cases ( n  = 9), R1 resections ( n  = 41), and survival of
ISSN:1068-9265
1534-4681
1534-4681
DOI:10.1245/s10434-013-3204-2