Biological and Immunological Aspects of Innate Defence Mechanisms Activated by (1,3)- β -Glucans and Related Polysaccharides in Invertebrates

(1,3)- β -glucans are powerful stimulants of a wide variety of innate defence reactions in invertebrates. These polysaccharides exert a great influence on reactions such as induction of antimicrobial peptides, cellular defence such as encapsulation and phagocytosis, and on the melanization and coagu...

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Hauptverfasser: Cerenius, Lage, Kawabata, Shun-ichiro, Söderhäll, Kenneth
Format: Buchkapitel
Sprache:eng
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Zusammenfassung:(1,3)- β -glucans are powerful stimulants of a wide variety of innate defence reactions in invertebrates. These polysaccharides exert a great influence on reactions such as induction of antimicrobial peptides, cellular defence such as encapsulation and phagocytosis, and on the melanization and coagulation cascades. In most cases, these reactions set up an effective defence against microorganisms containing (1,3)- β -glucans or (1,3;1,6)- β -glucans in their outer structures (i.e. mainly fungi and oomycetes).