Substrate Modulation of the Activity of an Artificial Nanoesterase Made of Peptide-Functionalized Gold Nanoparticles

Substrate Modulation of the Activity of an Artificial Nanoesterase Made of Peptide-Functionalized Gold Nanoparticles

Nanozymes with a heart of gold: A functional artificial protein has been prepared by grafting a dodecapeptide onto the surface of gold nanoparticles (see picture). The system catalyzes the hydrolysis of carboxylate esters and features enzyme‐like properties.

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Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2007-01, Vol.46 (3), p.400-404
Hauptverfasser: Pengo, Paolo, Baltzer, Lars, Pasquato, Lucia, Scrimin, Paolo
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acid Sequence
artificial proteins
Catalysis
Chemistry
Esterases - chemistry
Esterases - metabolism
gold
Gold - chemistry
Hydrogen-Ion Concentration
Hydrolysis
Kemi
Molecular Sequence Data
Molecular Structure
nanoparticles
Nanoparticles - chemistry
NATURAL SCIENCES
NATURVETENSKAP
peptides
Peptides - chemistry
Peptides - metabolism
Substrate Specificity
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Beschreibung
Zusammenfassung:Nanozymes with a heart of gold: A functional artificial protein has been prepared by grafting a dodecapeptide onto the surface of gold nanoparticles (see picture). The system catalyzes the hydrolysis of carboxylate esters and features enzyme‐like properties.
ISSN:1433-7851
1521-3773
1521-3773
DOI:10.1002/anie.200602581