The interaction of wood nanocellulose dressings and the wound pathogen P. aeruginosa
•CNF hydrogels indicated dose-dependent inhibition of P. aeruginosa.•CNF wound dressing does not increase the virulence factors production by P. aeruginosa.•The biofilm growth is affected by the surface and bulk structure of the assessed CNF dressings. Chronic wounds pose an increasingly significant...
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Veröffentlicht in: | Carbohydrate polymers 2017-02, Vol.157, p.1955-1962 |
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Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | •CNF hydrogels indicated dose-dependent inhibition of P. aeruginosa.•CNF wound dressing does not increase the virulence factors production by P. aeruginosa.•The biofilm growth is affected by the surface and bulk structure of the assessed CNF dressings.
Chronic wounds pose an increasingly significant worldwide economic burden (over £1 billion per annum in the UK alone). With the escalation in global obesity and diabetes, chronic wounds will increasingly be a significant cause of morbidity and mortality. Cellulose nanofibrils (CNF) are highly versatile and can be tailored with specific physical properties to produce an assortment of three-dimensional structures (hydrogels, aerogels or films), for subsequent utilization as wound dressing materials. Growth curves using CNF (diameter 0.05) over 24h. These data demonstrate the potential of nanocellulose materials in the development of novel dressings that may afford significant clinical potential. |
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ISSN: | 0144-8617 1879-1344 1879-1344 |
DOI: | 10.1016/j.carbpol.2016.11.080 |