Renal preservation in children with neurogenic bladder–sphincter dysfunction followed in a national program

Abstract Purpose Neurogenic bladder–sphincter dysfunction (NBSD) constitutes the major reason for morbidity in children with spina bifida. The aim of this study was to identify risk factors for renal damage in children with NBSD followed according to the Swedish national guidelines. Materials and Methods Records and cystometries from 6 to 16 years (median 11) follow up of 41 consecutive children born 1993–2003 with NBSD were evaluated. The children were divided into a high pressure group (baseline pressure above 30 cmH2 O at maximal clean intermittent catheterization volume in at least two cystometries) and a low pressure group. Most children (34/41) were followed from birth. Results Although renal scarring on DMSA-scintigraphy was found in 5/41 children, all but one had normal renal function. Two already had renal scars on entering the follow-up program at age 2.5 and 3 years. Renal scarring was more frequent in the high pressure group ( P