Limitations of Intraoperative Adrenal Remnant Volume Measurement in Patients Undergoing Subtotal Adrenalectomy

Background Recent studies have shown that a minimum of approximately one-third of one normal adrenal gland is required for sufficient adrenocortical stress capacity. Correlation between intraoperative measurement, determination of remnant size by computed tomography (CT), and adrenocortical stress c...

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Veröffentlicht in:World journal of surgery 2008-05, Vol.32 (5), p.863-872
Hauptverfasser: Brauckhoff, Michael, Stock, Karsten, Stock, Susanne, Lorenz, Kerstin, Sekulla, Carsten, Brauckhoff, Katrin, Thanh, Phuong Nguyen, Gimm, Oliver, Spielmann, Rolf Peter, Dralle, Henning
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Sprache:eng
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Zusammenfassung:Background Recent studies have shown that a minimum of approximately one-third of one normal adrenal gland is required for sufficient adrenocortical stress capacity. Correlation between intraoperative measurement, determination of remnant size by computed tomography (CT), and adrenocortical stress capacity has not been examined so far. Methods Twenty-two patients with familial pheochromocytoma (n = 13), sporadic pheochromocytoma (n = 3), and adrenocortical tumors (n = 6) who underwent unilateral or bilateral subtotal adrenalectomy (STAE, 28 adrenal remnants) were prospectively studied. Patients were examined in a multi-slice CT to determine residual adrenal tissue and by ACTH test 4 days and 3 months postoperatively. Results There was a slight significant correlation between intraoperative and CT calculated volumes ( r  = 0.77; p  
ISSN:0364-2313
1432-2323
1432-2323
DOI:10.1007/s00268-007-9402-y