Increased arterial stiffness in males with abdominal aortic aneurysm

Background Abdominal aortic aneurysm (AAA), a localized dilatation of the abdominal aorta, has a prevalence of about 1.5%–3% among 65‐ to 70‐year‐old males in Europe. AAA confers an increased risk of developing major cardiovascular events in addition to the risk of aneurysm rupture. The aim of this...

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Veröffentlicht in:Clinical physiology and functional imaging 2021-01, Vol.41 (1), p.68-75
Hauptverfasser: Åström Malm, Ida, De Basso, Rachel, Blomstrand, Peter, Bjarnegård, Niclas
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Sprache:eng
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Zusammenfassung:Background Abdominal aortic aneurysm (AAA), a localized dilatation of the abdominal aorta, has a prevalence of about 1.5%–3% among 65‐ to 70‐year‐old males in Europe. AAA confers an increased risk of developing major cardiovascular events in addition to the risk of aneurysm rupture. The aim of this study was to evaluate whether the arterial wall distensibility is altered in subjects with AAA. Methods Two hundred and eighty‐four male subjects (182 with AAA and 102 controls) were enrolled in the study. Arterial wall distensibility was evaluated using non‐invasive applanation tonometry to measure regional pulse wave velocity between the carotid and femoral arteries and the carotid and radial arteries. In addition, blood pressure was measured, and the pulse pressure waveform was analysed. Results Higher aortic augmentation index (25.1% versus 20.6%; p 
ISSN:1475-0961
1475-097X
1475-097X
DOI:10.1111/cpf.12667