Dysregulated growth hormone‐insulin‐like growth factor‐1 axis in adult type 1 diabetes with long duration

Dysregulated growth hormone‐insulin‐like growth factor‐1 axis in adult type 1 diabetes with long duration

Summary Context In type 1 diabetes (T1D), dysregulation of the GH‐IGF‐1 axis has been reported. Whether this is related to upper extremity impairments (UEI) is unknown. Objective Examine differences in GH‐IGF‐1 axis between T1D on subcutaneous insulin treatment and matched controls without diabetes...

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Veröffentlicht in:Clinical endocrinology (Oxford) 2018-10, Vol.89 (4), p.424-430
Hauptverfasser: Gutefeldt, Kerstin, Hedman, Christina A., Thyberg, Ingrid S.M., Bachrach‐Lindström, Margareta, Spångeus, Anna, Arnqvist, Hans J.
Format: Artikel
Sprache:eng
Schlagworte:
Blood glucose
Diabetes
Diabetes mellitus
Diabetes mellitus (insulin dependent)
Fasting
Growth hormones
Insulin
Insulin resistance
Insulin secretion
Insulin-like growth factors
insulin‐like growth factor‐1
insulin‐like growth factor‐binding protein‐1
Laboratory testing
Patients
Population studies
Secretion
type 1 diabetes
upper extremity impairments
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Zusammenfassung:Summary Context In type 1 diabetes (T1D), dysregulation of the GH‐IGF‐1 axis has been reported. Whether this is related to upper extremity impairments (UEI) is unknown. Objective Examine differences in GH‐IGF‐1 axis between T1D on subcutaneous insulin treatment and matched controls without diabetes and possible associations between GH‐IGF‐1 axis and UEI. Design Cross‐sectional population‐based study. Patients with T1D, onset
ISSN:0300-0664
1365-2265
1365-2265
DOI:10.1111/cen.13810