Quality of Life as an Independent Predictor for Cardiac Events and Death in Patients With Heart Failure

Background: Little is known about health-related quality of life (QOL) in Japanese patients with heart failure. The purpose of this study was to identify factors related to QOL using a disease-specific QOL instrument, and to clarify whether QOL independently predicts clinical outcomes among Japanese...

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Veröffentlicht in:Circulation Journal 2011, Vol.75(7), pp.1661-1669
Hauptverfasser: Kato, Naoko, Kinugawa, Koichiro, Seki, Satomi, Shiga, Taro, Hatano, Masaru, Yao, Atsushi, Hirata, Yasunobu, Kazuma, Keiko, Nagai, Ryozo
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Sprache:eng
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Zusammenfassung:Background: Little is known about health-related quality of life (QOL) in Japanese patients with heart failure. The purpose of this study was to identify factors related to QOL using a disease-specific QOL instrument, and to clarify whether QOL independently predicts clinical outcomes among Japanese patients with heart failure. Methods and Results: A total of 114 outpatients with heart failure were enrolled (mean age 64.7±15.8 years; 73.7% males). The Minnesota Living with Heart Failure Questionnaire (MLHFQ) to assess patient's QOL was used. At baseline, depressive symptoms and chronic kidney disease were significantly associated with worse QOL in multiple regression analysis. During a 2-year follow up, patients with a MLHFQ score ≥26, indicating worse QOL, had a higher incidence of the combined endpoint of cardiac death or hospitalization for heart failure, and a higher all-cause mortality than those with a score
ISSN:1346-9843
1347-4820
1347-4820
DOI:10.1253/circj.CJ-10-1308