Asymmetric radical additions of trialkylboranes to 2H-azirine-3-carboxylates

Asymmetric additions of alkyl radicals, generated from R3B, to chiral 2H-azirine-3-carboxylates offer a new entry to enantio-enriched aziridines, and proceed with high diastereoselectivity when using 8-phenylmenthol as chiral auxiliary.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2004-09, Vol.10 (18), p.2088-2089
Hauptverfasser:	Risberg, Erik, Fischer, Andreas, Somfai, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	2h-azirines amino-acids chiral aziridines convenient dienophiles organoboranes synthetic applications
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Asymmetric additions of alkyl radicals, generated from R3B, to chiral 2H-azirine-3-carboxylates offer a new entry to enantio-enriched aziridines, and proceed with high diastereoselectivity when using 8-phenylmenthol as chiral auxiliary.
ISSN:	1359-7345 1364-548X 1364-548X
DOI:	10.1039/b408532a