Chemical copying of connectivity: DNA nanotechnology
Three-dimensional DNA nanoscaffolds such as supramolecular tetrahedra can self-assemble from tris-oligonucleotidyls — synthetic three-armed building blocks in which three identical or non-identical short DNA sequences are connected by a tris-linking backbone 1 , 2 . Here we show that the connectivit...
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| Veröffentlicht in: | Nature (London) 2002-11, Vol.420 (6913), p.286-286 |
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| container_issue | 6913 |
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| container_title | Nature (London) |
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| creator | Eckardt, Lars Henning Naumann, Kai Matthias Pankau, Wolf Rein, Michael Schweitzer, Markus Windhab, Norbert von Kiedrowski, Günter |
| description | Three-dimensional DNA nanoscaffolds such as supramolecular tetrahedra can self-assemble from tris-oligonucleotidyls — synthetic three-armed building blocks in which three identical or non-identical short DNA sequences are connected by a tris-linking backbone
1
,
2
. Here we show that the connectivity information contained in these building blocks can be copied by using template-directed tris-linking. This finding is a crucial step towards the replication of nanoarchitectures that are based on tris-oligonucleotidyls and to the realization of artificially self-replicating systems on a nanometre scale. |
| doi_str_mv | 10.1038/420286a |
| format | Article |
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1
,
2
. Here we show that the connectivity information contained in these building blocks can be copied by using template-directed tris-linking. This finding is a crucial step towards the replication of nanoarchitectures that are based on tris-oligonucleotidyls and to the realization of artificially self-replicating systems on a nanometre scale.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/420286a</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>brief-communication ; Humanities and Social Sciences ; multidisciplinary ; Science ; Science (multidisciplinary)</subject><ispartof>Nature (London), 2002-11, Vol.420 (6913), p.286-286</ispartof><rights>Springer Nature Limited 2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/420286a$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/420286a$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27922,27923,41486,42555,51317</link.rule.ids></links><search><creatorcontrib>Eckardt, Lars Henning</creatorcontrib><creatorcontrib>Naumann, Kai</creatorcontrib><creatorcontrib>Matthias Pankau, Wolf</creatorcontrib><creatorcontrib>Rein, Michael</creatorcontrib><creatorcontrib>Schweitzer, Markus</creatorcontrib><creatorcontrib>Windhab, Norbert</creatorcontrib><creatorcontrib>von Kiedrowski, Günter</creatorcontrib><title>Chemical copying of connectivity: DNA nanotechnology</title><title>Nature (London)</title><addtitle>Nature</addtitle><description>Three-dimensional DNA nanoscaffolds such as supramolecular tetrahedra can self-assemble from tris-oligonucleotidyls — synthetic three-armed building blocks in which three identical or non-identical short DNA sequences are connected by a tris-linking backbone
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1
,
2
. Here we show that the connectivity information contained in these building blocks can be copied by using template-directed tris-linking. This finding is a crucial step towards the replication of nanoarchitectures that are based on tris-oligonucleotidyls and to the realization of artificially self-replicating systems on a nanometre scale.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><doi>10.1038/420286a</doi></addata></record> |
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| language | eng |
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| subjects | brief-communication Humanities and Social Sciences multidisciplinary Science Science (multidisciplinary) |
| title | Chemical copying of connectivity: DNA nanotechnology |
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