Gastroschisis: A Successful, Prospectively Evaluated Treatment Model in a Middle-Income Country

Background This research adopted a care protocol from high-income countries in a level II/III hospital in a middle-income country to decrease morbidity and mortality associated with gastroschisis. Methods We established a multidisciplinary protocol to treat patients with gastroschisis prospectively from November 2012 to November 2018. This included prenatal diagnosis, presence of a neonatologist and pediatric surgeon at birth, and either performing primary closure on the patients with an Apgar score of 8/9, mild serositis, and no breathing difficulty or placing a preformed silo, when unable to fulfill these criteria, under sedation and analgesia (no intubation) in the operating room or at the patients’ bedside. The subsequent management took place in the neonatal intensive care unit. The data were analyzed through the Mann–Whitney and Student’s t -distribution for the two independent samples; the categorical variables were analyzed through a chi-square distribution or Fisher’s exact test. Results In total, 55 patients were included in the study: 33 patients (60%) were managed with a preformed silo, whereas 22 patients (40%) underwent primary closure. Prenatal diagnosis ( P = 0.02), birth at the main hospital ( P = 0.02), and the presence of a pediatric surgeon at birth ( P = 0.04) were associated with successful primary closure. The primary closure group had fewer fasting days ( P