Detection of the presence of antibodies against

More than people in the United States and people in Mexico probably are infected with the parasite, but very few have symptoms because the immune system usually keeps the parasite from causing illness. However, for people whose immune system is compromised, the consequences can be fatal. Toxoplasmos...

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Veröffentlicht in:Journal of Biomedical Optics 2007-06, Vol.12 (3), p.034006-034005
Hauptverfasser: Araujo-Andrade, Cuauhtemoc, Pichardo-Molina, Juan L, Barbosa-Sabanero, Gloria, Frausto-Reyes, Claudio, Torres-Lo´pez, Angelica
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Sprache:eng
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Zusammenfassung:More than people in the United States and people in Mexico probably are infected with the parasite, but very few have symptoms because the immune system usually keeps the parasite from causing illness. However, for people whose immune system is compromised, the consequences can be fatal. Toxoplasmosis is detected indirectly by different serological tests, where the sample requires a previous preparation. We analyze the feasibility to use Raman spectroscopy and principal component analysis (PCA) as an alternative method to detect the presence or absence of antibodies IgG (immunoglobulin G), IgM (immunoglobulin M), and IgA (immunoglobulin A), against , in a simple and fast way, in samples of human colostrum from a group of volunteers who were in contact with the parasite and others who were not in contact with the parasite.
ISSN:1083-3668
1560-2281
DOI:10.1117/1.2749740