Evaluation of β-carotene isolated from Rhodoturella sp. as anti-cancer agents

Microorganisms that produce pigment are among the natural sources that have the ability to help solve today’s problems. Additionally, natural colors have additional benefits like anti-oxidant and anti-cancer ca-pabilities. In the present article we analyze the biological and clinical characteristics of microbial pigments, such as their anticancer capabilities. so, this study, β-carotene was extracted from Rhodoturella yeast using acetenone as a dye solvent and investigated the therapeutic potential of β-carotene as an anticancer agent. Where the anticancer efficacy was tested using colon and bladder cancer cell lines results demonstrate the efficient method of the extraction and the cytotoxicity of β-carotene purified from Rhodoturella sp. Each cell line of bladder and colon cancer was exposed to different concentrations of β-carotene (0.3215, 0.625, 1.25, 2.5, 10) mg/ml, and estimated the cytotoxicity by finding the percentage of growth inhibition compared to the control group considering their growth rate100.0%.