Light exposure’s effects on inactive frequency and distance moved of zebrafish insomnia model

Insomnia is inability to maintain or elevate sleep quality at least three times a day, more than three days in a week, or more than three months. One of theories that is explaining insomnia causes focuses on a condition called hyperarousal, which is related to increasing mental, cognitive, and motor activities. This study was applied to create the insomnia model, that zebrafish larvae were exposed to ilumination with intensity of 200 lux. There were four phases of light exposure, consist of 12 hours of light with 12 hours of dark, and 18 hours of light with 6 hours of flash. The flash phase group was divided into two groups consit of 2 minutes light on with 2 minutes dark and 4 minutes light on with 1 minute dark. The result showed that the 24-hour treatment, both light and dark cycles, have a lower inactive frequency and a higher distance moved compared to the control group.