Bactericidal hydrosols’ properties of metal nanoparticles and their oxides in relation to escherichia coli

The article presents the results of in vitro studies of metal hydrosols conducted by the suspension method to determine antimicrobial activity against the gram-negative microorganism Escherichia coli, which is an indicator of bacteria in determining the disinfection quality. The studies were carried out in accordance with the current regulatory document GOST R 59072-2020. National Standard of the Russian Federation. Disinfectants. Suspension method for determining antimicrobial activity. The test culture of Escherichia coli was acquired in the laboratory of diagnostics and control of antibiotic resistance of the most clinically significant infectious diseases’ animal pathogens of the Federal State Budgetary Institution of the Federal Research Center of Experimental Veterinary of the Russian Academy of Sciences. According to the results of the studies, the authors found that the studied metal hydrosols prevent the growth of E. coli on dense Endo and meat infusion agar media; the results were recorded after 24 and 48 hours of cultivation in a thermostat at a temperature of 37.0 °C. Except for the Ag + sodium citrate hydrosol (E 331), the growth of the culture from the 3rd to the 5th cultivation on the Endo medium was noted. The data obtained allow to recommend the above-mentioned metal hydrosols for use at veterinary supervision facilities as disinfectants.